Please use this identifier to cite or link to this item: http://repository.uinjkt.ac.id/dspace/handle/123456789/48922
Title: ANTIHYPERGLYCEMIC EFFECT AND GLUCOSE TOLERANCE OF ETHANOL EXTRACT THE RIND OF JENGKOL (PITHECOLLOBIUM JIRINGA JACK) IN DIABETIC RATS
Other Titles: The 2nd International Integrative Conference on Health, Life and Social Sciences (ICHLAS 2018)
Authors: Muhammad Yanis Musdja
Weldy Marison
Ahmad Musir
Keywords: International Seminar;Pharmacy (Jengkol for Antidiabetes)
Issue Date: 21-Oct-2018
Publisher: State Islamic University (UIN), Syarif Hidayatullah, Jakarta
Series/Report no.: PROGRAM BOOK;Natural Product
Abstract: In traditional medicine, the rind of jengkol or skin of jengkol fruit (Pithecellobium jiringa Jack) has been used by some people to reduce blood glucose levels in some districts of Indonesia. This study aims to determine the antihyperglycemic effect and glucose tolerance of ethanol extract of the rind of jengkol (Pithecollobium jiringa Jack) in diabetic rats. Jengkol fruit was bought from Kebonjeruk market, West Jakarta and determination of jengkol rind was done at the Biology Research Center, Indonesian Institute of Sciences, Bogor.Indonesia. Jengkol rind was separated from the fruit seeds. Preparation of jengkol rind extract was done by cold maceration extraction technique using ethanol 70%. The male albino rats that qualify for the experiment were made into diabetics using the alloxan method. The rats were divided into 7 groups, each group consisted of 5 rats. as positive control for anti-diabetic was used glibenclamide and for glucose tolerance test was used acarbose, as normal control just given aqudest and for negative control wass given a solution for suspending the test preparation (1% CMC Na). For extract of jengkol rind was given low dose ( 24,5 mg/200 gr bw), medium dose (49 mg/200 gr bw) and high dose (196 mg/200 gr bw) and glucometer tool was used to measure blood sugar levels. Statistical results with ANOVA test and Kruskal-wallis test showed that small and medium doses of jengkol rind extract had the same antidiabetic effect and glucose tolerance with positive control and nt to negative Keywords antidiabetes, jengkol rind, male rats, Pithecollobium Jiringa Jack, tolerance glucose.
Description: This study aims to determine the antihyperglycemic effect and glucose tolerance of ethanol extract of the rind of jengkol (Pithecollobium jiringa Jack) in diabetic rats.
URI: http://repository.uinjkt.ac.id/dspace/handle/123456789/48922
Appears in Collections:Prosiding Workshop/Lokakarya/Seminar



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