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Title: Genetic pattern of CYP1A1*2A (T>C) gene in patients with colorectal cancer in South Jakarta – Indonesia
Authors: Chris Adhiyanto
Witri Ardini
Hoirun Nisa
Zeti Harriyati
Dina A. Amu
Kemal A.L. Fajar
Taslim Poniman
Rofi Saunar
W. Aditomo
Keywords: CYP1A1*2A;colorectal cancer;Indonesia
Issue Date: Dec-2017
Publisher: Atlantis Press
Abstract: The information of relationship between genetics and cancer in Indonesia, especially colon cancer, is still limited. This study aimed to determine the genetic pattern of colon cancer allele in Fatmawati Hospital, Jakarta -Indonesia. We conducted a case-control study of 40 colorectal cancer patients and 133 volunteers as controls. We observed CYP1A1*2A alleles using RFLP-PCR method. Three milliliters of blood was used to isolate DNA. Our observation showed of the genetic patterns CYP1A1*2A with the incidence of colorectal cancer showed 17 patients were variant-type homozygote and 12 patients were heterozygote type. Conclusions: In this research shown the common of genotyping type CYP1A1*2A of colorectal cancer from the patients are a heterozygous variant type.
ISSN: 2468-5739
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1.c.1 Tahun 2017 Genetic pattern of CYP1A1_2A.pdf915.67 kBAdobe PDFView/Open
1.c.1 Genetic CYP1A1-5-11.pdf28.52 kBAdobe PDFView/Open
1.c.1 Genetic pattern of CYP1A1_2A (PR).pdf802.99 kBAdobe PDFView/Open

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